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TERATEC 2025 Forum
The European meeting for Experts in High Power Digital
Simulation . HPC/HPDA . Artificial Intelligence . Quantum Computing

Wednesday May 21
Workshop 04 - 4:15 pm to 6:15 pm

HPC, AI and quantum digital technologies in healthcare
Chaired by Yves Vandenbrouck, Research Director, CEA and Christian Saguez, Co-founder and Honorary Chairman, Teratec

Will AI decipher the shapes of our brains?
By Jean-François Mangin, Research Director, CEA / Neurospin

The shapes of the folds of our cortex and the underlying tangle of axon bundles are as unique to each of us as our fingerprints. These shapes are sculpted during brain development. They are not under pure genetic control. Their variability is so complex that modeling them is largely beyond human comprehension. The first generations of AI that assisted neuroscientists over the last few decades have made some progress, but they are intrinsically limited by the narrow vision of human experts. The huge digital databases available today will enable us to overcome these limitations by designing self-supervised AIs capable of revealing a hidden language, indicating, for example, developmental weaknesses that increase the risk of psychiatric pathology. This research program, which currently manipulates over 100,000 brains, requires considerable computing power. The gigabyte image describing the wiring of a single brain is stored over several tens of gigabytes.

Biographie : Jean-François Mangin has spent his entire career in neuroimaging at the CEA. For the past 30 years, his main research program has focused on deciphering the variability of cortical folds using AI techniques (https://sites.google.com/view/jfmangin/). He currently heads Neurospin's UMR BAOBAB, a neuroimaging research center with the world's most powerful MRI, and the national UMS CATI, dedicated to multi-center neuroimaging collection for clinical research. He is also responsible for the French node of the EBRAINS infrastructure.

 

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